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Scientist, Cancer Biology

CHARM Therapeutics is a biotech company focused on delivering transformational medicines that will address difficult-to-drug targets in key oncogenic pathways.
CHARM has developed the first highly accurate, high throughput protein-ligand co-folding algorithm (DragonFold), driven by end-to-end 3D deep learning. Our platform enables the rapid generation of highly differentiated clinical candidates, and our ambition is to revolutionise drug discovery.

CHARM Therapeutics is establishing a state-of-the-art R&D facility in Cambridge, UK.  We are currently seeking a Biologist with a passion for scientific innovation to join the Cancer Biology group at CHARM Therapeutics. You will help increase the biological understanding of programs as well as generating key data for compound evaluation required to help propel our programs forward. Your role will be comprised of:


  • Running routine assays for development of a therapeutic agent
  • Novel target identification and validation
  • Working in a matrixed team
  • Communicating with team members across functions


The successful candidate will join a multidisciplinary, highly collaborative discovery team to invent novel medicines and drive them towards the clinic.


Role Requirements

You are a highly motivated individual with excellent communication and interpersonal skills, who is effective at working in a collaborative and diverse environment. You have a MSc degree in one of the following fields – molecular biology, cell biology, biochemistry, pharmacology or a related field and have:


  • A background in oncology and ability to understand the biology around novel targets and pathways to test scientific hypothesis
  • Experience using molecular biology techniques, including but not limited to PCR, Western blotting, and ELISAs
  • Additional experience in running routine biochem/biophys assays such as fluorescence, luminescence, FRET and DSF/thermal shift assays is a plus.
  • High level of competence working in a cell culture laboratory and using cell-based assays to evaluate biological mechanisms
  • Excellent ability to analyse, write up and communicate experimental results
  • Proactive and organised with the ability to work independently as well as part of a team
  • Able to work in a highly flexible environment


What We Offer


  • Private medical insurance, including dental cover
  • Competitive pension scheme
  • Gym membership
  • Weekly team lunch
  • Office fruits & snacks
  • Regular socials